Brain research bulletinAnimalsSevofluraneRatsBrainOligodendrocyte Precursor Cells
Kir4.1-mediated immunophenotypic OPCs underlies sevoflurane-induced hypomyelination in the developing brain.
Liping Sun, Luping Feng, Yuxin Zhang, Mengqin Shan, Chaoyang Tong, Kan Zhang, Jijian Zheng, Xin Fu
Published: 202510.1016/j.brainresbull.2025.111564
Abstract
Clinical and animal experimental studies demonstrate that prolonged or repeated general anesthesia (GA) impairs myelination in the developing brain. However, the underlying cellular mechanisms remain unclear. Oligodendrocyte precursor cells (OPCs), a…
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