Brain researchAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Cancer PainSpinal Cord Dorsal HornBone Neoplasms
The mechanism of Calhm2 regulating the expression of CaMKIIα in spinal dorsal horn involved in the pathogenesis of bone cancer pain.
Mengyuan Xiong, Xiaohui Li, Shanchun Su, Xueqin Xu, Jiaqi Yu, Wei Tian, Linhan Wang, Changbin Ke
Published: 202610.1016/j.brainres.2026.150158
Abstract
Bone cancer pain (BCP) is one of the most common and debilitating types of pain in cancer patients, severely impairing the quality of life in advanced stages of the disease. However, its underlying mechanisms remain poorly understood, highlighting th…
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