Biological psychiatry. Cognitive neuroscience and neuroimaging
Linking Estradiol Timing and Tempo, Brain Development, and Mental Health Problems in Adolescent Females.
Muskan Khetan, Nandita Vijayakumar, Ye Ella Tian, Sarah Whittle
Published: 202510.1016/j.bpsc.2025.10.006
Abstract
BACKGROUND: Earlier timing and faster tempo of puberty have been associated with altered brain development and increased mental health problems in adolescents, particularly females. However, the role of estradiol (E2) in these associations is unclear…
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