Biophysical journal
A moments-based approach for inferring mechanisms of transcriptional regulation using nascent RNA data.
Kunwen Wen, Yu Liao, Jiandong Wang, Sandeep Choubey, Feng Jiao
Published: 202610.1016/j.bpj.2026.01.030
Abstract
Unraveling the kinetics of transcriptional regulation is a central challenge in molecular biology. Traditional inference methods based on cell-to-cell mRNA variability are limited because mRNA levels reflect not only transcriptional activity but also…
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