Biophysical journal
Single-molecule force measurements show that r-proteins assist 23S rRNA co-transcriptional folding.
Lena Melkonyan, Thierry Bizebard, Ryo Aoyama, Takuya Ueda, Ulrich Bockelmann
Published: 202610.1016/j.bpj.2026.01.001
Abstract
Mechanical overstretching of individual RNA-DNA hybrids is used as a novel in vitro assay to prepare a co-transcriptional RNA structure and study its interaction with proteins. Dual optical traps hold two microscopic beads linked by an RNA-DNA molecu…
Preview only. Read the full abstract at the source