Biophysical journalSorting NexinsMolecular Dynamics SimulationProtein MultimerizationCell MembraneProtein Binding
Division of labor in cargo and membrane recognition by SNX1-SNX5: Insights from multiscale modeling.
Satya Chaithanya Duggisetty, Gaurav Kumar, Krishnakanth Baratam, Anand Srivastava
Published: 202610.1016/j.bpj.2025.11.004
Abstract
Sorting nexins (SNXs) are a large group of diverse cellular trafficking proteins that play essential roles in membrane remodeling and cargo sorting between organelles. SNX proteins comprise a banana-shaped BAR domain that acts as a curvature-inducing…
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