Biophysical journalRotationMolecular Dynamics SimulationMonte Carlo MethodProton-Translocating ATPasesProtein Domains
Structural basis for efficient Fo motor rotation revealed by MCMD simulation and structural analysis.
Shintaroh Kubo, Hiroyuki Noji
Published: 202610.1016/j.bpj.2025.10.006
Abstract
Fo domain of ATP synthase functions as a rotary molecular motor, coupling proton translocation with the rotation of the c-ring rotor. This process involves proton uptake at the entry half-channel, rotor rotation, and proton release to the exit half-c…
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