Biophysical journal
Modeling mechanochemical coupling in optogenetically activated cell layers.
Dennis Wörthmüller, Falko Ziebert, Ulrich S Schwarz
Published: 202510.1016/j.bpj.2025.10.002
Abstract
In adherent cells, actomyosin contractility is regulated mainly by the RhoA signaling pathway, which can be controlled by optogenetics. To model the mechanochemical coupling in such systems, we introduce a finite element framework based on the discon…
Preview only. Read the full abstract at the source