Biophysical journal
Tool antibody fragments reveal multiple conformations of the rhodopsin-Gi signaling complex.
Filip Pamula, Oliver Tejero, Jonas Mühle, Ralf Thoma, Gebhard F X Schertler, Jacopo Marino, Ching-Ju Tsai
Published: 202510.1016/j.bpj.2025.09.044
Abstract
Antibody Fab fragments are widely used protein binders that assist in structural studies of G-protein-coupled receptor (GPCR) signaling complexes. Expanding the repertoire of such binders to target distinct components of the signaling complex offers…
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