Bone
Prmt1-mediated methylation of Ddx17 promotes osteoblast differentiation via regulating the alternative splicing of Sh2b1.
Xinluan Jiang, Bilan Li, Yunfei Ma, Jiaxin Huang, Chengwei Gu, Yucui Jin, Huimin Ding, Changyan Ma
Published: 202610.1016/j.bone.2026.117798
Abstract
Osteoporosis (OP) is characterized by impaired osteoblast-mediated bone formation and reduced mineralization, which increases fracture risk and challenges global skeletal health. Ddx17 (DEAD-box helicase 17) is implicated in multiple cancers, but its…
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