Bone
Integrated methylome and hydroxymethylome analysis identifies CAMK2G, NFATC4, and SFRP2 as TET1-regulated drivers of odontoblastic differentiation in human dental pulp cells.
Qimeng Li, Jinling Li, Deqian Zhang, Qiong Xu
Published: 202610.1016/j.bone.2026.117775
Abstract
AIM: DNA 5-methylcytosine (5mC) dynamics are pivotal for tooth differentiation. However, the 5mC landscape during human dental pulp cell (hDPCs) odontoblastic differentiation and the role of Ten-eleven translocation 1 (TET1)-mediated 5mC regulation r…
Preview only. Read the full abstract at the source