BoneAnimalsOsteogenesisOsteomyelitisStaphylococcus aureusOsteoclasts
CTLA4-Ig sustains osteogenic potential and inhibits osteoclastogenesis in Staphylococcus aureus osteomyelitis.
Rongjie Lin, Yiqing Huang, Zhenbin Chen, Xi Zeng, Yao Wang, Shaohuang Weng, Yu Cheng, Min Chen
Published: 202610.1016/j.bone.2025.117731
Abstract
Osteomyelitis (OM) is a severe bone-destructive disease characterized by infection and inflammation. Transcriptomic analysis of datasets GSE18043 and GSE30119 identified CTLA4 as a key regulator associated with immune modulation and osteogenic differ…
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