BoneOsteocytesCell DifferentiationAnimalsGlucoseMice
Osteocyte differentiation requires glucose metabolism, but mature osteocytes display metabolic flexibility.
Matthew Prideaux, Mathilde Palmier, Yukiko Kitase, Yuika Sone, Lynda F Bonewald, Thomas M O'Connell
Published: 202610.1016/j.bone.2025.117694
Abstract
Recent research has identified metabolic pathways which play key roles in the differentiation and function of osteoblasts and osteoclasts. However, the mechanisms by which osteocytes, the most numerous cells in bone, meet their energetic demands are…
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