Bioorganic & medicinal chemistry letters
Discovery of multitargeting single agents as a novel route to the potential treatment of neurodegenerative diseases.
Jeetal Vyas, Anuj S Jamenis, Krishna Kaku, Yesha Shah, Kristin M Miner, Tarun N Bhatia, Roxanne E Kim, Ruoli Bai, Ernest Hamel, Rehana K Leak, Aleem Gangjee
Published: 202610.1016/j.bmcl.2026.130536
Abstract
There are no cures for neurodegenerative diseases. The biggest hurdle to treating these disorders is that their clinical manifestation is rooted in multiple physiological processes. Therefore, efficacious pharmaceutical options will likely require tw…
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