Bioorganic & medicinal chemistry lettersAbietanesMast CellsAnimalsMiceAnti-Allergic Agents
Synthesis of dehydroabietic acid derivatives as mast cell stabilizers.
Tao Zeng, Wenchao Yu, Chenming Gu, Jian-Guo Fu, Motahareh Asgari, Yiming Li, Fei Qian, Chen-Guo Feng
Published: 202610.1016/j.bmcl.2025.130477
Abstract
Mast cell degranulation plays a central role in IgE-driven allergic diseases, yet the therapeutic options for stabilizers remain limited. Rosinane diterpenoids, a class of natural polyphenols known for their anti-inflammatory properties, represent an…
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