Bioorganic & medicinal chemistry letters
Improved synthesis and anti-inflammatory activity of new fluorinated dihydropyranonaphthoquinone compounds.
Quynh Giang Nguyen Thi, Ha Thanh Nguyen, Tuyet Anh Dang Thi, Kieu Trinh Nguyen Thi, Giang Le-Nhat-Thuy, Phuong Hoang Thi, Tuan Anh Nguyen, Mai Dang Thi, Ha Nguyen Thi Thu, Hoang Sa Nguyen, Tuyen Van Nguyen
Published: 202510.1016/j.bmcl.2025.130434
Abstract
This study presents the synthesis of new fluorinated dihydropyranonapthoquinone compounds by means of microwave-prompted four-component reactions using lawson, fluorinated aromatic aldehydes, ethyl 4,4,4-trifluoroacetoacetate and ammonium acetate. Th…
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