Bioorganic & medicinal chemistryStructure-Activity RelationshipAntitubercular AgentsMycobacterium tuberculosisQuinazolinesMicrobial Sensitivity Tests
Structure-activity relationship study of a new class of 2-amino-3,4-dihydroquinazolines as antitubercular agents.
Lena Trifonov, Helena I Boshoff, Jose Santinni O Roma, Yixuan Fan, He Eun Forbes, Clifton E Barry, Sangmi Oh
Published: 202610.1016/j.bmc.2026.118549
Abstract
The discovery of novel chemical matter with antitubercular activity that could feed into the tuberculosis (TB) drug discovery pipeline addresses the need to develop novel drugs that inhibit growth of both drug sensitive and drug resistant strains of…
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