Bioorganic & medicinal chemistryProdrugsHumansAntineoplastic AgentsNeoplasmsReactive Oxygen Species
Exogenous/endogenous stimuli-responsive antitumor prodrugs advance precision chemotherapy.
Luo Wang, Jingao Li, Xuanwei Zeng, Qinyue Lu, Yifeng Wang, Zulhumar Anwar, Li Xue, Heli Fan, Huabing Sun
Published: 202610.1016/j.bmc.2025.118485
Abstract
Precision chemotherapy aims to selectively target cancer cells while sparing healthy cells, thereby addressing a major challenge in traditional chemotherapy, off-target toxicity. Stimuli-responsive antitumor prodrugs leverage exogenous or endogenous…
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