British journal of anaesthesia
Prophylactic norepinephrine infusion to reduce severe hypotension during induction of anaesthesia in patients undergoing cardiac surgery: a randomised controlled single-centre clinical trial.
Come Gaillard, Lea Breul, Adrien Foucher, Jean-Christophe Rigal, Charles-Henri David, Fouzia Souab, Manon Canevet, Mael Ryan, Arthur Bailly, Hélène Morin, Julien Cadiet, Cloé Geay, Bertrand Rozec, Mickael Vourc'h
Published: 202510.1016/j.bja.2025.10.055
Abstract
BACKGROUND: The EPITUBE trial aimed to determine whether a prophylactic infusion of norepinephrine reduced severe hypotension after induction of general anaesthesia and tracheal intubation in patients undergoing cardiac surgery. METHODS: We performed…
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