Biomedical journal
Anti-PD-L1 improves barrier function and reduces CD103+ DC cell accumulation by regulating gut and lung microbiota and its metabolites to alleviate asthma in juvenile mice.
Jinli Huang, Yi Zhang, Qiuhong Li, Min Wang, Han Zhou, Hui Su, Xin Sun
Published: 202510.1016/j.bj.2025.100944
Abstract
BACKGROUND: Programmed death ligand 1 (PD-L1) was found to play an important role in maintaining tolerance and immune balance, and its mechanism of action on asthma still needs to be further clarified. We aim to block P MATERIAL AND METHODS: in a juv…
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