Biosensors & bioelectronicsHumansNucleic Acid Amplification TechniquesBiosensing TechniquesLab-On-A-Chip DevicesClass I Phosphatidylinositol 3-Kinases
A droplet digital LAMP-based lab-on-a-disc system for multiplex allele-specific detection of tumor-derived DNA mutations.
Hui Lu, Qin Wang, Xun Tang, Yu Jiang, Jianjiang Shen, Xiao Yang, Ning Jiang, Xiaoming Wang, Feng Yan
Published: 202610.1016/j.bios.2025.118367
Abstract
The absence of accurate, rapid, fully automated, and cost-effective detection methods has hindered the clinical translation of tumor-derived DNA mutations as cancer biomarkers. Here, we develop a sample-to-answer platform, termed multiplexed droplet…
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