Biosensors & bioelectronics
Mitochondrial microRNA detection using a sequentially activatable allosteric DNA biosensor for in vivo molecular visualization of tumors and tumor drug resistance.
Jingzhe Zang, Tingting Wang, Fei Zhang, Mengxin Zhang, Mengmeng Chen, Kangbo Liu, Xianwei Zhang, Hong Qin, Ying Xu, Wancun Zhang
Published: 202510.1016/j.bios.2025.118046
Abstract
The development of strategies that enable in situ detection of mitochondrial microRNA (miRNA) remains a significant challenge, as miRNA is widely distributed across various cellular compartments. Therefore, by utilizing the mitochondria-specific loca…
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