Bioresource technologyLigninGene EditingLipidsMicrofluidicsBioreactors
Integrated base editing and microfluidics boost microbial lipid production from lignin.
Changyu Pi, Jinyang Li, Tongtong Bao, Le Gao, Xin Wu
Published: 202610.1016/j.biortech.2025.133441
Abstract
Lignin, a recalcitrant aromatic biopolymer, is a promising feedstock for sustainable valorization. Here, we investigated the transcriptional response of Curvularia clavata J1 to alkali lignin (AL) and established a Cu2+-inducible MCM5-AID base editor…
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