Biological psychiatry
The relationship between family history of depression and brain structure and function: a systematic review of large cohorts.
James O Woodruff, Tenzin Yangchen, Nora C Kelsall, Myrna M Weissman, Laura Beth McIntire, Ardesheer Talati, Milenna T van Dijk
Published: 202610.1016/j.biopsych.2026.01.006
Abstract
Family history (FH) of major depression is a well-replicated risk factor for developing the disorder. Studying individuals who may be at high familial risk but are symptom free may allow us to better distinguish mechanisms predisposing individuals to…
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