Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ampelopsin preserves glutamate homeostasis against cerebral ischemia.
Zhen Li, Fang Li, Wang Song, Chun-Mei Long, Xin Zeng, Wen-Kai Guo, Bin Chen, Tai-Xin Jia, Li Lu
Published: 202610.1016/j.biopha.2026.119002
Abstract
The glutamate (Glu)-glutamine (Gln) cycle between astrocytes and neurons plays a crucial role in maintaining extracellular Glu levels during excitatory neurotoxicity, with glutamine synthetase (GS) and glutaminase (GLS) serving as the key enzymes. Am…
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