Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Deciphering the interaction between osteosarcoma and mesenchymal stem cells in a 3D bone-mimetic co-culture model.
Giada Bassi, Mohamed Saqawa, Lorenzo Apolloni, Silvia Díaz-Prado, Emilie Ollivier, Romain Levergeois, Monica Sandri, Elisabetta Campodoni, Denis Cochonneau, Silvia Panseri, Dominique Heymann, Monica Montesi
Published: 202610.1016/j.biopha.2025.118956
Abstract
Osteosarcoma (OS) is a highly heterogeneous and aggressive bone malignancy whose complexity is strongly influenced by its Tumor Microenvironment (TME). Within this niche, Mesenchymal Stem Cells (MSCs) play a pivotal role in tumor progression by under…
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