Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieHumansHashimoto DiseaseAntigensDifferentiationB-Lymphocyte
An emerging role of CD74 in thyroid follicular cells in Hashimoto´s thyroiditis.
Pablo Sacristán-Gómez, Ana Serrano-Somavilla, Nuria Sánchez de la Blanca, Andrea Álvarez-Rodríguez, Eduardo Martínez-Parra, Miguel Sampedro-Nuñez, Fernando Sebastián-Valles, Mónica Marazuela, Rebeca Martínez-Hernández
Published: 202610.1016/j.biopha.2025.118945
Abstract
Autoimmune thyroid disorders (AITD), including Hashimoto's thyroiditis (HT) and Graves' disease (GD), arise from disrupted immune tolerance to thyroid antigens. In HT, thyroid follicular cells (TFCs) are central to disease pathogenesis and exhibit in…
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