Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieHumansProtein-Arginine Deiminase Type 4NeoplasmsCaffeic AcidsLactates
The binding of the salvianolic acid A to the citrullinating enzyme PADI4 as a potential treatment for cancer.
Laureano E Carpio, María Gabriela Álvarez-Rodríguez, David Recio-Moreno, Felipe Hornos, Izabel Georgieva-Nikolova, Ana Camara-Artigas, Virginia Rejas, Miguel Vidal, Martina Palomino-Schätzlein, Camino de Juan Romero, José L Neira
Published: 202610.1016/j.biopha.2025.118935
Abstract
Cancer cells must maintain molecular mechanisms relying on an energy trade-off between resistance and key functions to survive. PADI4 (peptidyl arginine deiminase 4) is an enzyme implicated in the conversion of arginine to citrulline (citrullination)…
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