Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieHumansCurcuminHCT116 CellsAntineoplastic AgentsCell Survival
Curcumin-based benzothiazepane analogues exhibit selective anti-cancer activity in HCT-116 cells via precipitated particle formation and internalisation.
Julie De Munck, Charlotte Grootaert, Katarina Magdalenic, Derya Deveci, Yannick Gansemans, Filip Van Nieuwerburgh, Nico Boon, Andre Skirtach, Andreja Rajkovic, Matthias D'hooghe, John Van Camp
Published: 202610.1016/j.biopha.2025.118926
Abstract
Despite extensive investigation into the anti-cancer activity of the natural polyphenol curcumin, its therapeutic application is restricted by its inherent physicochemical properties. Synthetic curcumin analogues, however, offer a promising strategy…
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