Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieAnimalsDeoxyadenosinesGastrointestinal MicrobiomeCellular SenescenceMice
Elucidation of mechanisms underlying the therapeutic effects of cordycepin on pulmonary hypertension, with a focus on cell senescence and gut microbiota.
Gaopeng Li, Zhixin Zhao, Mitsuhiro Machitani, Ryou Ishikawa, Kaori Ishikawa, Naoya Yokota, Reiji Haba, Kazufumi Nakamura, Zhihong Sun, Lin-Hai Kurahara, Katsuya Hirano
Published: 202610.1016/j.biopha.2025.118923
Abstract
INTRODUCTION: Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder characterized by excessive pulmonary vascular remodeling and aberrant proliferation of pulmonary artery smooth muscle cells (PASMCs). Emerging evidence suggests that…
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