Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieAnimalsApigeninMicrogliaGlucuronatesExosomes
Exosome-mediated scutellarin delivery enhances BBB penetration and microglia targeting in antiviral neuroprotection.
Chunlian Song, Shengjia Sun, Ting Li, Ke Zhang, Xiong Zhao, Zee Zhu, Deng Pan, Huayi Bai, Ying Zhang, Deyan Cui, Limei Yang, Xiaoyu Liu, Xianghua Shu
Published: 202610.1016/j.biopha.2025.118903
Abstract
Scutellarin, the active component of Erigeron breviscapus(Vant.)Hand.-Mazz, has therapeutic potential for neurological diseases but is limited by poor solubility, low bioavailability, and inability to cross the blood-brain barrier (BBB). This study u…
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