Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieAlzheimer DiseaseAmyloid beta-Peptidestau ProteinsHumansMolecular Docking Simulation
In silico virtual screening of natural small molecules for dual inhibition of Aβ and tau aggregation in Alzheimer's disease.
Sujin Kim, Vijay Kumar, Soo Jung Shin, Yunkwon Nam, Yong Ho Park, Sinae Jang, Jun Young Park, Dong Hyun Kim, Minho Moon
Published: 202510.1016/j.biopha.2025.118876
Abstract
Alzheimer's disease (AD) is defined by the accumulation of amyloid beta (Aβ) plaques and twisted fibers of hyperphosphorylated tau, with their aggregation driving neurodegeneration and cognitive decline. Presently, the majority of therapies in develo…
Preview only. Read the full abstract at the source