Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieHumansCarcinomaRenal CellImmune Checkpoint InhibitorsKidney Neoplasms
Immune checkpoint inhibition in renal cell carcinoma: Mechanisms of resistance and emerging therapeutic strategies.
Ali Darzi, Mahla Shokouhfar, Narges Farajee, Arezoo Ghafari, Fatemeh Deldar, Pooya Eini, Ahmad Ghorbani Vanan, Nastaran Bahrami
Published: 202510.1016/j.biopha.2025.118875
Abstract
Renal cell carcinoma (RCC) represents a major therapeutic challenge due to its highly immunosuppressive tumor microenvironment. Over the past decade, immune checkpoint inhibitors (ICIs) have revolutionized the management of advanced RCC, shifting tre…
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