Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Targeting of Kaposi's sarcoma-associated herpesvirus by immunotoxins directed against the viral G protein-coupled receptor, ORF74.
Dagmar Fæster Kildedal, Anna Katarzyna Drzazga, Anjali Sharma, Christian Berg, Astrid Norup Winther, Laura Krogh-Hansen, Martin Gustavsson, Birthe B Kragelund, Jon Våbenø, Michael Lagunoff, Naotaka Tsutsumi, Thomas N Kledal, Mads G Jeppesen, Mette M Rosenkilde
Published: 202610.1016/j.biopha.2025.118797
Abstract
BACKGROUND AND PURPOSE: Kaposi's sarcoma-associated herpesvirus (KSHV) is a common virus with severe outcome and no effective antiviral treatment. KSHV encodes the constitutive active chemokine receptor ORF74 with broad-spectrum CXC-chemokine binding…
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