Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieDihydropyridinesRenal InsufficiencyChronicAnimalsMatrix Metalloproteinase 7
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
Chia-Te Liao, Yen-Chung Lin, Hung-Jin Huang, Wen-Chih Liu, Wei-Chih Kan, Hui-Wen Chiu
Published: 202510.1016/j.biopha.2025.118748
Abstract
Matrix metalloproteinases (MMPs) are a critical family of proteolytic enzymes responsible for extracellular matrix (ECM) remodeling and degradation. Among them, MMP7 has emerged as a key regulator in the pathogenesis of kidney diseases, exerting a mo…
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