Effects of isoflurane on tetrodotoxin-resistant Na⁺ channels in rat nociceptive sensory neurons: Roles of concentration and extracellular pH.

Isoflurane is widely employed to induce unconsciousness, amnesia, immobility, and analgesia in general anesthesia. Voltage-gated Na+ channels are one of the molecular targets for volatile anesthetics; however, knowledge regarding how isoflurane modul…

Preview only. Read the full abstract at the source