Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieNLR FamilyPyrin Domain-Containing 3 ProteinHumansInflammasomesPulmonary Fibrosis
Emerging roles of NLRP3 inflammasome-mediated pathways in pulmonary fibrosis: Current knowledge and therapeutic strategies.
Can Xiao, Yanfei Xie, Xiang Liu, Haibo Lei
Published: 202510.1016/j.biopha.2025.118717
Abstract
Pulmonary fibrosis (PF) is a highly disabling and fatal chronic lung disease with limited treatment options. Chronic inflammation is considered a crucial pathological mechanism underlying the initiation and progression of PF. The NLRP3 inflammasome p…
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