Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieCell DifferentiationMyocytesCardiacHumansRegeneration
Cardiac regeneration revisited: Enhanced cardiomyocyte differentiation and repair through composite microenvironments and small molecules.
Manizheh Azhdari, Shahram Rabbani, Nader Tanideh, Safieh Boroumand
Published: 202510.1016/j.biopha.2025.118642
Abstract
BACKGROUND: The generation of mature, functional cardiomyocytes from human pluripotent stem cells (hPSCs) remains a major challenge in cardiac regenerative medicine. While fibronectin and Matrigel individually support cardiomyocyte differentiation, t…
Preview only. Read the full abstract at the source