Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieHumansComplement Factor HLigandsComputational BiologyProtein Binding
Structural characterization of Factor H via computational methods: Implications for disease and therapy.
Atala Bihari Jena, Asim K Duttaroy
Published: 202510.1016/j.biopha.2025.118628
Abstract
Complement Factor H (CFH) is a crucial regulator of the alternative complement pathway, maintaining immune balance by preventing excessive activation that damages host tissues. This liver-derived glycoprotein binds to C3b and inhibits C3 convertase f…
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