Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieAnimalsBrain-Derived Neurotrophic FactorGlucosidesCadmiumSignal Transduction
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside against cadmium toxicity involve BDNF/TrkB and PI3K/Akt signaling pathways.
Run-Ze Gu, Abduwares Tursun, Si-Jia Zhong, Jin-Bo Cheng, Xiao-Yan Qin, Chang Cao
Published: 202510.1016/j.biopha.2025.118602
Abstract
Polygonum multiflorum is a traditional Chinese medicinal herb used to nourish the blood, promote hair growth, and support neurological health. Its key bioactive component, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG), has shown potent antio…
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