Bioorganic chemistry
An insight into the anticancer potential of sulfonated styrylquinazolines as multifunctional agents targeting microtubules.
Patryk Rurka, Jacek Mularski, Patryk Ziola, Anna Boguszewska-Czubara, Josef Jampilek, Anna Mrozek-Wilczkiewicz, Katarzyna Malarz
Published: 202610.1016/j.bioorg.2026.109517
Abstract
Developing new microtubule-targeting agents is extremely important for cancer treatment. One of the goals is to overcome drug resistance, since these agents can cause mitotic arrest and thus cause impairment to cell signaling. Despite this, there are…
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