Bioorganic chemistryMolecular Docking SimulationChalconesCholinesterase InhibitorsPyridinesAmyloid beta-Peptides
Novel bis-Thiazolidinone -based chalcones with pyridine linker: Eco-friendly synthesis, cholinesterase and beta-amyloid inhibition potency, and molecular docking studies.
Sobhi M Gomha, Sami A Al-Hussain, Sayed M Riyadh, Basant Farag, Tariq Z Abolibda, Marwan M Alrehaili, Hafsah M Alakhdhari, Magdi E A Zaki
Published: 202610.1016/j.bioorg.2025.109372
Abstract
The grinding technique is a mechanochemical method that avoids the use of solvents in the reaction mixture, thereby reducing the detrimental effects of vapour and affording an environmentally and economically efficient process. This technique was uti…
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