Bioorganic chemistryChitosanVancomycinWound HealingAntioxidantsAnimals
Bioengineered vancomycin-loaded chitosan/collagen nanocomposite from Sphyrna lewini: Antioxidant, antimicrobial, and antidiabetic applications in wound healing.
K Netha, R Karthick Raja, U Nithya, Gayathri Mahalingam, Sekar Vijayakumar, C Vinothini, Thandapani Gomathi, V Rekha
Published: 202610.1016/j.bioorg.2025.109352
Abstract
This study aimed to develop a vancomycin (VCM)-loaded chitosan nanoparticle (CS-NPs)/collagen (Col) composite for the treatment of diabetic foot ulcers. Collagen was isolated as acid-soluble collagen (ASC) from the skin of Sphyrna lewini shark and co…
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