Bioorganic chemistryDiterpenesMicrogliaNF-kappa BAnimalsLipopolysaccharides
Casbane diterpenoids from Euphorbiaceae suppresse neuroinflammation by regulating microglia polarization via inhibiting NF-κB signaling.
Baojun Su, Yaqi Wang, Haiyan Zhao, Yongli Zhang, Hengshan Wang, Guijie Zhang, Yan Wang, Dong Liang
Published: 202610.1016/j.bioorg.2025.109347
Abstract
Phytochemical investigation of Triadica rotundifolia and Neoshirakia japonica resulted in the discovery of eight new casbane diterpenoid derivatives. The structures of all isolates were structurally characterized by comprehensive spectroscopic techni…
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