Bioorganic chemistryHumansMuramidaseMolecular Docking SimulationCyproterone AcetateAmyloid
Off-target molecular recognition of cyproterone acetate by human lysozyme: conformational remodelling, enzyme modulation, and amyloid inhibition.
Vanshika, Gulafsha, Kehkashan Naaz, Sukriti Maurya, Suhel Parvez, Basir Ahmad
Published: 202510.1016/j.bioorg.2025.109273
Abstract
Cyproterone acetate (CPA), a synthetic steroidal antiandrogen, is widely used in clinical therapy. However, its off-target interactions with non-receptor proteins remain inadequately explored. Here, we investigated the molecular recognition of CPA by…
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