Bioorganic chemistryHumansParkinson DiseaseDopamine Plasma Membrane Transport ProteinsBenztropineAnimals
Development of benztropine-based DAT blockers for Parkinson's disease interventions: A biologic and synthetic overview.
Edson D Hernández-Velázquez, Rubén Chávez-Rivera, Rafael Ortíz-Alvarado, César R Solorio-Alvarado
Published: 202610.1016/j.bioorg.2025.109245
Abstract
Parkinson's disease is considered a neurodegenerative brain affection where the substantia nigra, a group of dopamine producer neurons are eliminated and hence, dopamine levels go to dangerous lower levels. With this molecule limited, an imbalance in…
Preview only. Read the full abstract at the source