Bioorganic chemistryAnti-Bacterial AgentsBiofilmsSulfonamidesPseudomonas aeruginosaMicrobial Sensitivity Tests
Novel 2-oxoethylthio-sulfonamide derivatives targeting pyocyanin/staphyloxanthin producing-pathogens: Antibiofilm, DHPS inhibition and gamma radiation effects.
Mostafa M Ghorab, Dina S Aboul-Magd, Aiten M Soliman
Published: 202510.1016/j.bioorg.2025.109228
Abstract
A series of sulfonamide acetamide derivatives 3-14 were synthesized and evaluated for their antibacterial and anti-virulence activities. The target compounds were initially screened in vitro for their antibacterial activity against multidrug-resistan…
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