Bioorganic chemistryLipopolysaccharidesHMGB1 ProteinMiceAnimalsRAW 264.7 Cells
Microbial transformation of Soyasapogenol C and potential of its metabolites against HMGB1 and LPS-triggered inflammation.
Libang Zhang, Guolong Li, Richa Raj, Boyang Yu, Jian Zhang, Hao Wu, Pingping Shen
Published: 202510.1016/j.bioorg.2025.109208
Abstract
Soyasapogenol C, a oleanane-type pentacyclic triterpenoid, is mainly derived from soybean and its residual cake after oil extraction. Herein, microbial transformation of soyasapogenol C by Bacillus megaterium CGMCC 1.1741 and Streptomyces griseus ATC…
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