Bioorganic chemistryHumansCell ProliferationUp-RegulationMembrane ProteinsDisease Progression
R-loop accumulation promotes OSCC malignant progression by upregulating MARVELD3 expression.
Xinyi Li, Xuerong Xiang, Jiao Huang, Tingxiu Xiang, Ping Ji
Published: 202510.1016/j.bioorg.2025.109180
Abstract
OBJECTIVE: The R-loop is known to play a critical role in the progression of various cancers, yet its involvement in OSCC remains unexplored. This study aims to investigate the role and mechanism of R-loop-mediated MARVELD3 in OSCC. METHODS: DRIP-seq…
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