Bioorganic chemistryAnimalsHumansAntiparkinson AgentsDrug RepositioningMolecular Structure
Therapeutic innovation through drug repurposing: A multidimensional approach toward treating Parkinson's disease.
Saswati Swagatika Sahoo, Sudhir Kumar Paidesetty, Pratap Kumar Sahu, Swagata Pattanaik, Rambabu Dandela
Published: 202510.1016/j.bioorg.2025.109129
Abstract
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer's disease, primarily affecting the aging population. Despite the introduction of levodopa in the 1960s and significant progress in managing PD symptoms,…
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